LINK CK8 OPTIONS

In addition, UPEC co-opts ferritinophagy (a selective method of autophagy) and shuttles into the autophagosomal and lysosomal compartments with ferritin-bound iron, facilitating UPEC survival and persistence throughout the urothelium280. Autophagy commonly leads to bacterial degradation, but UPEC can block acidification and endure in lysosomes281.